Recent advances in glioblastoma multiforme therapy: A focus on autophagy regulation
| 期刊 | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie |
| 发表日期 | 2022-Nov |
| 作者 | Sanati Mehdi; Binabaj Maryam Moradi; Ahmadi Seyed Sajad; Aminyavari Samaneh; Javid Hossein; Mollazadeh Hamid; Bibak Bahram; Mohtashami Elmira; Jamialahmadi Tannaz; Afshari Amir R; Sahebkar Amirhossein |
| DOI | 10.1016/j.biopha.2022.113740 |
| PMID | 36166963 |
原始摘要
Despite conventional treatment options including chemoradiation, patients with the most aggressive primary brain tumor, glioblastoma multiforme (GBM), experience an average survival time of less than 15 months. Regarding the malignant nature of GBM, extensive research and discovery of novel treatments are urgently required to improve the patients' prognosis. Autophagy, a crucial physiological pathway for the degradation and recycling of cell components, is one of the exciting targets of GBM studies. Interventions aimed at autophagy activation or inhibition have been explored as potential GBM therapeutics. This review, which delves into therapeutic techniques to block or activate autophagy in preclinical and clinical research, aims to expand our understanding of available therapies battling GBM.
| 撤稿日期 | 2026-08 |
| 撤稿期刊 | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie |
| 发布机构 | France |
| 通知PMID | 42342505 |
Retraction notice to "Recent advances in glioblastoma multiforme therapy: A focus on autophagy regulation" [Biomedicine & Pharmacotherapy 155 (2022) 113740]